Endocrine Abstracts

Introduction: Primary amyloidosis is a multi-systemic disease difficult to identify given the diversity of the disorders that it can cause especially at an early stage of the disease. This makes its diagnosis difficult in case of association with a pathology that can be intricate with its clinical expression. In this context we report the first case in the literature associating mitochondrial diabetes (DM) with a primary amyloidosisCase: A 32 years old g...

IntroductionMitochondrial diabetes (DM) is characterized by a broad spectrum of phenotypic and genotypic involvement. Among 86 patients with DM, we chose to study the peculiarities of syndromic DM diagnosed in three families in order to be able to establish a correlation between this diversity of phenotypic expression and the biomolecular substratum of the mitochondrial genome.ResultsThese are four patients (...